MultiStress – Concurrent Multiple Abiotic and Biotic Stress Interactions in Maize: Impacts and Mechanisms 

The DFG Research Unit (RU) 6101 investigates the complex interactions of combined stress factors in order to secure global food production across temperate and tropical environments. The RU pioneers climate-resilient agriculture by revolutionising the mechanistic understanding of the interactions between abiotic and biotic stress in maize – with a focus on the field scale. To this end, it integrates knowledge from the genetic to the field scale, combining field trials, high-throughput multi-omics, and process-based crop modelling.

Understanding the Complexity of Concurrent Stresses

We conduct novel research on concomitant multiple abiotic and biotic stress interactions and their impacts on maize. As advancing global warming increasingly leads to situations of multiple stress in farmers’ fields, this research is highly relevant to prevent massive yield losses and meet the pressing challenges of food security and climate change. 

To close key knowledge gaps, we conduct a coordinated research project under field conditions to investigate how the combined effects of drought and nitrogen deficiency, alongside the foliar disease Setosphaeria turcica and the stem borer, impact the growth, yield, and stover quality of maize. To improve our mechanistic/process-based understanding of such interactions at different organisational levels (from the genetic via biochemical to the ecophysiological/field level), we will establish and utilise common field experimental platforms (rain-out shelters (ROUTS)), and, in parallel, conduct satellite experiments under controlled conditions.

In the Central Experiments (CE), six carefully selected commercial maize hybrid genotypes will be investigated in the ROUTS in Germany (DE) and Kenya (KE) over three field seasons. This enables a comparison of the crop stress responses of maize hybrids from temperate and tropical climate zones under different environmental conditions. These CE experiments will be complemented by diversity screening experiments in the greenhouse and in the field to assess the variability of stress response mechanisms in highly diverse maize populations – using high-throughput transcriptomics as well as metabolomics.

Closely interlinked with these experiments, process-based crop growth simulation modelling forms the second pillar of our research. Crop simulation models enable the integration of new knowledge (obtained at various organisational levels, ranging from the genetic to the ecophsiological /field level) as well as the extrapolation of this knowledge  across time and space.

In the RU, the formalisation of our improved interdisciplinary mechanistic/process-based understanding of the interactions between multiple stresses under field conditions enables us to quantify the overall impact of combined (abiotic + biotic) stresses on crop physiology and productivity (grain yield, biomass, grain and stover quality, nutrient/water use efficiency, etc.). This requires that new modelling routines derived from experiments (representing formalised knowledge) be incorporated into basic process-based crop simulation models.  The resulting MultiStress crop model will be applied to test the research unit’s (RU’s) basic hypotheses in silico, and to support the design of further experiments. The newly aquired (formalised) knowledge can be used to explore promising traits for stress-tolerant breeding, which should be considered in the ideotyping of resilient maize cultivars for future target environments – in temperate and tropical zones (as planned for Phase 2 of the RU).

Multi-Stressed Maize

Diagram showing factors affecting maize—Setosphaeria infection, stem borer damage, water and nitrogen deficits—impacting defence mechanisms and crop yield, modelled to support climate-resilient agriculture and food security.

MultiStress Research News

Upcoming MultiStress Relevant Events

03.-08.05. 2026
Confernce contribution: EGU2026 at Vienna, Austria
Presentation Prof. Rötter in Session BG 3.22, Modeling agricultural systems under global change, 7 May, 16:15 h on Multistress experimental and modelling approach 
01.- 03.09.2026
Confernce contribution: GPZ at Halle, Germany
Keynote of Prof. Rötter about the MultiStress Research Unit  
07.-09.09.2026
Outreach day: Deutsches Mais Komittee at Göttingen, Germany
Overview of Research Group MultiStress FOR 6101 – First Results of Preliminary Experiments
10.09.2026
Confernce contribution: Gesellschaft für Pflanzenbauwissenschaften e. V. at Hohenheim, Germany
Keynote of Prof. Rötter about establishing a linked modelling and experimental platform for maize  
16.-17.09. 2026
Confernce contribution: Tropentag 2026 (TT26) at Göttingen, Germany
Workshop on enhanced resilience of multi-functional maize smallholder systems in the tropics
06.-08.10.2026
Kick-Off at Bondo, Kenya
Briefly describe the timeline event providing your audience with all the details they need to know about it.
22.-27.02.2026
Confernce contribution: AgMIP 11 at ILRI, Nairobi, Kenya
Satellite meeting AgMIP-maize . Presentation Prof. Rötter & M Mugarura on planned Multistress maize model intercomparison exercise on water and nitrogen dynamics
Research Unit Metrics

MultiStress In A Nutshell

Principal Investigators
Co-Principal Investigators
Collaboration partners
PhD students
Field trial sites
Rain out shelters & greenhouse trials

MultiStress is coordinated by the University of Göttingen. Together with 9 other research institutions, we are working on understanding the complexity of concomitant multiple abiotic and biotic stress interactions in tropical and temperate maize.

Quick Navigation → MultiStress Research Unit

Discover the central project, coordination project & 6 subprojects

A glasshouse showcasing climate-resilient agriculture, with tall green plants inside, two large water tanks on either side, and a partly cloudy sky above.

ZP – Central Project

Microscopic view of a plant root with thin, branching root hairs against a light pink background, highlighting structures crucial to ecophysiology and Multi-Stress Research.

SP1

A potted maize plant is positioned in front of a black backdrop, with a camera on a tripod set up to photograph it in a glasshouse for ecophysiology research.

SP2

Several potted maize plants growing in a controlled environment chamber with green trays and reflective metal walls, supporting MultiStress Research and crop modelling studies.

SP3

A close-up of a green leaf with round holes and bite marks, held by a brown clip—an example studied in MultiStress Research to advance climate-resilient agriculture, with potted plants blurred in the background.

SP4

Close-up of a maize leaf with brown streaks and discolouration, indicating signs of disease or stress—valuable insight for MultiStress Research and climate-resilient agriculture—with other maize plants and a clear sky in the background.

SP5

A dirt path runs between tall rows of green maize plants under a clear blue sky, highlighting the role of crop modelling in advancing food security.

SP6

People sit around tables in a library or meeting room, attending a hybrid meeting with several participants visible on a large screen via video call, discussing topics like climate-resilient agriculture and food security.

COP – Coordination Project

Some Research Impressions